The scientific rationale

The scientific rationale:

The mechanism identified to slow the accumulation of dead neurons involves a known receptor with described activation and inhibition pathways. In neurons, activation of this receptor induces a type of programmed cell death called apoptosis.

Activation of this receptor is triggered when it interacts with a molecule from an already apoptotic neighboring neuron. It is this exponential accumulation of dead neurons that can be stopped by specifically blocking the activation of this receptor on the neurons still alive. I has been shown that blocking this receptor in the brain leads to neuroprotection.

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Preliminary results

The development plan